The exon-52-deleted mdx52 mouse is a critical model of Duchenne muscular dystrophy (DMD), as it features a deletion in a hotspot region of the DMD gene, frequently mutated in patients.Deletion of exon 52 impedes expression of several brain dystrophins (Dp427, Dp260 and Dp140), thus providing a key model for studying the cognitive impairment associa
AimTo evaluate the efficacy and tolerability of tetracycline vs.high-dose amoxicillin in bismuth-based quadruple therapy for Helicobacter pylori(H.pylori) eradication.MethodsThis randomized, open-label clinical trial included 228 patients with H.pylori infection and duodenal ulcer without a history of H.pylori treatment.Patients were randomly divid
The objective is to define the place of the operation of simple closure for perforated duodenal ulcers in the modern stage of the treatment of these patients.Material and methods.Comparative analysis of 2 groups of patients with perforated duodenal ulcer was made.The 1st group consisted of 40 patients who performed simple closure of perforated ulce